Isolation and characterization of dexamethasone-resistant mutants from human lymphoid cell line CEM-C7.
نویسندگان
چکیده
منابع مشابه
Characterization of a glucocorticoid-sensitive human lymphoid cell line.
A human lymphoblastoid cell line (CEM), the growth of which is inhibited by glucocorticoids, is described. Although growth of the original uncloned cell line is only slightly retarded by dexamethasone, sensitive clones were isolated in which growth is completely blocked by 2 to 3 days of exposure to 10(-6) M dexamethasone. After 4 to 5 days, these cells become pyknotic and lyse. The inhibitory ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1981
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.1.6.512